Pain Relievers: Eight Non-Opioid Types

If you’re suffering from headaches, muscle or joint pain or mild osteoarthritis, some medications can help. There are a variety of pain medications to choose from, and some types of pain relievers respond better to specific treatments than others. Because of this, you must make the appropriate decision to get the most out of your pain treatment. Each has its advantages and disadvantages, but professionals are available to assist you in determining the most appropriate form of pain management for your particular situation.

Your pharmacist is the first place to look for help. In many cases, they can assist you in determining the best course of action for your discomfort. You should see a physician if the pain you’re experiencing is severe enough to warrant a visit.

In addition to pharmaceuticals, there are non-medicated types of pain relievers that don’t have any active chemicals. These are commonly used to alleviate pain and reduce swelling by either heating or cooling the affected area.


NSAIDs (nonsteroidal anti-inflammatory drugs) can be bought over-the-counter (OTC) or prescribed only, depending on the type and strength of the medication. Nonsteroidal anti-inflammatory drugs (NSAIDs) can lower heat, edema, and inflammation and ease discomfort. Diclofenac, Ibuprofen, and Aspirin are the most commonly prescribed NSAIDs.

Natural Methods Of Treatment

There are numerous non-pharmacological options for treating pain in addition to prescription medications. Heating or cooling the area or joint in question is the primary mode of action for most of them. A heat pack can be used to alleviate back pain by boosting the flow of blood to the area where you are experiencing discomfort. Relaxation of the afflicted muscles can also be achieved.

The cold affects large nerve fibers, which temporarily block pain signals from being transferred to the smaller ones. By constricting the blood vessels, hard can minimize swelling and inflammation (a process called vasoconstriction). You can ice sports injuries to reduce swelling, including ankle and knee strains and sprains.

Eight Non-Opioid Types Of Pain Relievers

Eight Non-Opioid Types Of Pain Relievers

Ibuprofen (naproxen)

Naproxen is the generic name for the over-the-counter medicine sold under the brand name Aleve. Prostaglandins, the body’s pain-killing chemical, are inhibited by naproxen, a class of pharmaceuticals known as nonsteroidal anti-inflammatory drugs (NSAIDs). Prescriptions are required for more substantial concentrations of naproxen.

As a painkiller, Aleve can be used to treat a variety of ailments, including arthritis, menstrual cramps, back and neck pain, and headaches. Moreover, it can help lower fevers.

Adults should take 220 mg of Aleve orally every 8 to 12 hours while symptoms persist. For types of pain relievers, do not take Aleve for more than ten days at a time without consulting a doctor first.

There are possible adverse effects such as nausea, indigestion, diarrhea, and ringing in the ears.

Bayer’s Aspirin (Aspirin)

Generic Aspirin is marketed under the Bayer Aspirin brand name. Aspirin is a blood thinner and an NSAID. Pain, heat, and inflammation can be reduced by taking Aspirin.

Aspirin is commonly used to relieve the discomfort of migraines, menstrual cramps, and osteoarthritis.

Dosage: For short-term types of pain relievers, adults can take aspirin doses ranging from 325 mg to 650 mg once every four to six hours. Aspirin may be safe to take long-term if approved by a healthcare physician for cardiovascular health. Aspirin should only be used for minor aches, pains, and injuries on an as-needed basis.

Aspirin can induce stomach trouble, nausea, indigestion, and other adverse effects.

Advil And Motrin (Ibuprofen)

Ibuprofen is sold under the brand names Motrin and Advil. Another NSAID that may be purchased over-the-counter is Ibuprofen, which comes in various brand names and generic forms. Prescription-only Ibuprofen is also available at higher strengths. Inflammation and fevers are reduced.

With Ibuprofen, muscle aches, toothaches, arthritis pain, and other aches and pains can all be alleviated.

Taken orally, Ibuprofen’s recommended dosage for adults is between 200 and 400 mg every four to six hours. A doctor’s prescription is required if you plan to use Ibuprofen for more than ten consecutive days.

Diarrhea, nausea, and stomach distress are possible adverse effects of Ibuprofen.

Read About: When Pain Comes?

Aspirin, Ibuprofen, And Paracetamol (Acetaminophen)

Acetaminophen is a generic drug available over-the-counter under the brand name Tylenol. The types of pain relievers and fever reducer acetaminophen can be found in many over-the-counter medications (antipyretic).

Backaches, neck aches, toothaches, menstruation cramps, colds, sore throats, headaches, and minor injuries can all be treated with Tylenol.

Every four to six hours for the symptoms, adults should take 650 mg of Tylenol. Only take Tylenol if prescribed by a doctor for more than 10 days at once.

Acetaminophen can cause nausea, vomiting, sleeplessness, itching, and stomach pain, among other side effects.

Steroid Hormones

Hydrocortisone and prednisone are two of the most commonly given corticosteroids. Corticosteroids are prescribed anti-inflammatory medications for those who suffer from persistent pain and inflammation.

Corticosteroids can be used as types of pain relievers associated with osteoarthritis, rheumatoid arthritis, Crohn’s disease, and lupus, as well as other inflammatory conditions.

This depends on what the corticosteroid is being used for and the prescribed dosage. For long-term use, corticosteroids must be approved by a doctor.

The adverse effects include acne, mood changes, bruises and sleep disturbances, weight gain, fluid retention, and changes in blood sugar and blood pressure.

Muscle Relaxants

The central nervous system is sedated by muscle relaxants, which are more robust than over-the-counter types of pain relievers. Muscle spasms and cramps can be treated with them. Robaxin (methocarbamol) and Fexmid (methylphenidate) are two examples of regularly prescribed muscle relaxants (cyclobenzaprine).

Muscle relaxants can be helpful for persons with diseases such as neck pain, back pain, fibromyalgia, and multiple sclerosis.

How much a muscle relaxant should be taken depends on the patient is being prescribed it for.

Muscle relaxants may cause various undesirable side effects, including sleepiness, lethargy, dizziness, and changes in mood.

The Tricyclic Antidepressants

Antidepressants may be prescribed off-label for long-term pain because they alter how the brain processes pain. For the most effective pain relief, these drugs often take a few weeks to take effect. As amitriptyline and nortriptyline are tricyclic antidepressants, they impact the levels of serotonin and norepinephrine in the body.

Tricyclic antidepressants can be used as painkillers for diabetes neuropathy, arthritis, shingles, and fibromyalgia.

The dosage of a tricyclic antidepressant will vary depending on the type of pain and the cause. If prescribed by a doctor, tricyclic antidepressants are safe to take for long periods.

Dry mouth, dizziness, weight gain, sleepiness, and constipation are all possible side effects of these antidepressants.


Examples of anticonvulsant and antiepileptic medicines to alleviate nerve pain are Neurontin (gabapentin) and Lyrica (pregabalin). The burning sensation or stabbing nerve pain can be abrupt and intense. As a result, anticonvulsants can reduce or eliminate the sensation of pain.

Certain anticonvulsants can cure the nerve pain caused by diabetes, chemotherapy, fibromyalgia, shingles, or even the herpes virus.

Neurontin’s recommended dosage ranges from 300 to 1,200 mg three times a day for nerve pain. The recommended daily dosage of Lyrica for nerve pain treatment is between 300 mg and 600 mg.

Diarrhea, lack of coordination, sleepiness, weight gain and dry mouth are all possible adverse effects of Neurontin and Lyrica.

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