Pain Relievers: Their Action & Addictive Pain Killers

Painkillers, by their very nature, lose their effectiveness over time. Because your body will get used to the medication and develop a tolerance to it, you’ll need more significant doses to obtain the same effect.

The Action Of Paracetamol And Other NSAIDs

pain relievers

The effectiveness of paracetamol and NSAIDs in treating mild to moderate pain cannot be overstated.  Although they both alleviate pain, their mechanisms of action are somewhat distinct.

According to current research, paracetamol works mainly in the brain and affects a wide range of aspects of perceiving pain. Paracetamol, for example, blocks the formation of molecules known as prostaglandins, which cause pain and inflammation. When paracetamol is taken, it primarily affects prostaglandins in the brain—taking it as prescribed reduces the risk of adverse effects while also providing efficient relief from pain and fever. In addition, paracetamol has no anti-inflammatory action.

NSAIDs, on the other hand, such as ibuprofen and aspirin, function differently. Additionally, they halt the creation of prostaglandins, but not just in the brain. Prostaglandins, which play numerous additional roles in the body, can be affected by NSAIDs. This is made possible by a group of substances known as prostaglandins, which protect the stomach lining and the kidneys, keep the airways open, and the blood clotting normally.  Since NSAIDs block some prostaglandins, they help relieve pain. Still, even at over-the-counter (OTC) levels, they can interfere with producing other prostaglandins that our bodies need to function normally.

The larger prescription doses of NSAIDs that you get from your doctor (not the lesser over-the-counter ones) can help reduce inflammation when used for several weeks at a time. Consult your physician or pharmacist if you believe you require treatment to lessen inflammation.

Because NSAIDs and paracetamol function in distinct ways to reduce pain, these two forms of analgesics also differ significantly. Different side effects might occur and interactions with other medications (which can alter how a patient’s medication works). As a result, it’s critical that you always read the drug label before taking a pain reliever.

Painkillers That Are Addictive

Different drugs can be used to treat short-term or long-term pain. Opioid-based medications are prevalent in several of these products. Narcotic pain reliever medications include morphine, codeine, and a variety of synthetic variations of these medicines.

When taking painkillers, it is vital to exercise caution. Often, treatment can be more dangerous than the underlying problem causing discomfort. According to the recommendations on the label, taking painkillers lowers your chance of addiction, but it’s still possible to become dependent on them.

These drugs can still generate a “high” that some individuals can get addicted to. According to the National Institute on Drug Abuse (NIDA), this euphoria can lead to psychological dependence. Physical dependence is also a risk.


Actiq, Duragesic, and Sublimaze are among the most commonly prescribed fentanyl products, which are more potent than morphine.

There are fentanyl tablets, injections, and skin patches. Even though a doctor can prescribe it, the substance may also be unlawfully obtained. When it comes to fentanyl, common names include:

  • Apache
  • Chinese Girl
  • White China
  • It’s called “Dance Fever.”
  • Friend
  • Goodfella
  • Jackpot
  • The assassination of 8 People
  • In addition to Tango and Cash
  • TNT

Fentanyl is also commonly found in illegal substances like heroin and cocaine, combined with other chemicals to make them more potent. When people take these medicines, they may not realize that they contain fentanyl.

Drug Name: OxyContin

Extensive-release oxycodone is the brand name for OxyContin. Patients with moderate to severe pain who expect it to linger for an extended period can take it as a tablet and use it 24 hours a day, seven days a week. When OxyContin is sold illegally, it is referred to as O.C., Oxycet, Oxycotton, Oxy, or Hillbilly Heroin.

It’s Demerol

There is a generic term for meperidine called Demerol, a brand name for it. Anesthesia frequently necessitates the usage of this painkiller. Additionally, Demerol can manage moderate to severe pain (such as that which can be experienced after childbirth). An injectable solution and an oral tablet are also available. Demerol is referred to as Dummies and pain reliever on the streets.


In moderate to severe pain treatment, hydrocodone (sold under the trade names Vicodin, Norco, Zohydro, and others) is utilized. 11 Oral syrup and tablet versions are available. It is sometimes referred to as Vike or Watson-387 when marketed on the black market.


Duramorph and MS Contin are two popular brands of morphine, which is a natural opiate. It’s prescribed for people suffering from long-term pain (such as pain related to cancer or cancer treatment). It is possible to administer morphine through injection, pill or suppository. Although it’s also known as Miss Emma, Monkey, and White Stuff, Morphine is most commonly referred to as “M” on the street.

Percocet is: –

Percocet and OxyContin have a lot in common. Aspirin and oxycodone are found in it, known as Tylenol in the United States. It can be taken in a pill, tablet, or liquid. Hillbilly Heroin or “Percs” are two common street names for the drug.

In Terms Of Codeine: 

Natural opiate codeine is routinely administered to alleviate pain. This is why “Tylenol #3,” which contains acetaminophen or aspirin, is often administered in combination with it. Some prescription cough medications contain codeine as well. Tablets, capsules, and liquid codeine are all options for taking codeine. Codeine is sold under a variety of brand names and a variety of street names for both the drug itself and its many forms.

  • Cody:
  • Cody
  • Lean
  • Schoolboy
  • Sizzurp
  • Drank in a Purple Color


Most persons who use methadone are heroin addicts trying to kick the habit. The opiate analgesic properties of this drug can also be used, though.

Dolophine and Methadose are the brand names for two different forms of methadone: a tablet and a liquid solution. Amid one and Fizzies are two common street names for methadone. Combining it with MDMA, you get “Chocolate Chip Cookies.”

Buy Methadone Online


Hydromorphone is the generic name for Dilaudid. It is mainly utilized in hospitals, where it can be injected intravenously for short-term pain reliever (most often following a surgery). Oral solution, pill, and suppository forms of Dilaudid are all options for administering the drug. Illicitly, Dilaudid is referred to as “D.” Dillies, Footballs, Juice, and Smack are all other names for this substance.

An opioid: 

Opana, Numorphan, and Numorphone are all trade names for Oxymorphone. It is used to alleviate pain from moderate to severe.

There are immediate-release and extended-release tablet forms of the narcotic medication. An octagon-shaped pill in blue color is shown. As a result of the drug’s appearance, its most prevalent street names reflect this:

  1. Biscuits
  2. Heaven in the Blues
  3. Blues
  4. The Honorable Ms. O
  5. Explosion
  6. Octagons
  7. Stop Signs.


You should be aware of the addictive potential of pain relievers even if you are prescribed them for a good reason. Ask your doctor or pharmacist for advice when in doubt about a medicine.


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