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3-Hydroxyphenazepam is an active metabolite of the novel psychoactive benzodiazepine phenazepam, which emerged in online drug markets in late 2011. Despite being a controlled substance in Europe, North America, and many countries in Asia, phenazepam
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for instance, Phenazepam belongs to the 1,4-benzodiazepines, the same family of medicines to which diazepam, oxazepam and temazepam belong. It was first synthesize and develope in 1975 in the former Soviet Union where it became one of the most prescribe benzodiazepines since 1978 to treat sleep disorder, anxiety, alcohol use disorder and epilepsy. Phenazepam has not been license elsewhere in the world. The actions of phenazepam are mediate by the GABAA-receptor and reverse by the selective benzodiazepine antagonist flumazenil.
in addition to, Phenazepam increases the duration of sleep induce by hexanal several fold and is in this respect superior to diazepam. Both phenazepam and 3-hydroxyphenazepam are full GABAA receptor agonists.
Phenazepam is an anxiolytic and hypnotic sedative. 3-hydroxy Phenazepam is a major metabolite of phenazepam. There are significant differences in the rate of phenazepam metabolism in different species, so that 3-hydroxy phenazepam can be detect shortly after oral administration of the parent compound in cats, rats, and dogs but not in humans. The physiological and toxicological properties of this compound are not know. This product is intend for forensic and research applications.
in the same way, These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. \For a representative CofA please contact our technical support.
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